A part of low density lipoproteins (LDL) isolated from the blood of healthy subjects and
patients with coronary atherosclerosis bind to a Sepharose-linked Ricinus communis
agglutinin, a lectin that interacts specifically with galactose residues. Bound LDL can be
replaced by galactose, but not other saccharide constituents of the LDL molecule (mannose,
glucose, N-acetylglucosamine, sialic acid). Bound LDL subfraction has a 2–3-fold lower
content of sialic acid as compared with unbound LDL. The blood content of desialylated LDL …

Isolation of atherogenic modified (desialylated) low density lipoprotein from blood of
atherosclerotic patients : separation from native lipoprotein by affinity chromatography | CiNii
Research … Isolation of atherogenic modified (desialylated) low density lipoprotein from
blood of atherosclerotic patients : separation from native lipoprotein by affinity chromatography …